Maria Jönsson

PhD

Department of Environmental Toxicology
Uppsala University
Norbyvägen 18A
SE-752 36 Uppsala
Sweden

Phone: +46 18 471 2625
Fax: +46 18 51 88 43
E-mail: maria.jonsson@ebc.uu.se

Research

I am involved in the following projects:

MSc: Biology (Immunology), Stockholm University 1991

PhD: Environmental Toxicology, Uppsala University 2004

Postdoc: Stegeman laboratory, Woods Hole Oceanographic Institution (MA, USA) 2005-2007

Publications

Behrendt L, Jönsson ME, Goldstone JV and Stegeman JJ (2010) Induction of cytochrome P450 1 genes and stress response genes in developing zebrafish exposed to ultraviolet radiation. Aquat Toxicol, in press. PubMed link

Jönsson ME, Brunström B and Brandt I (2009) The zebrafish gill model: induction of CYP1A, EROD and PAH adduct formation. Aquat Toxicol. 91: 62-70. PubMed link

Jönsson ME, Franks DG, Woodin BR, Jenny MJ, Garrick RA, Behrendt L, Hahn ME and Stegeman JJ (2009) The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) binds multiple AHRs and induces multiple CYP1 genes via AHR2 in zebrafish. Chem Biol Interact. 181: 447-454. PubMed link

Abrahamson A, Andersson C, Jönsson ME, Fogelberg O, Örberg J, Brunström B and Brandt I (2007) Gill EROD in monitoring of CYP1A inducers in fish-A study in rainbow trout (Oncorhynchus mykiss) caged in Stockholm and Uppsala waters. Aquat Toxicol. 85: 1-8. PubMed link

Jönsson ME, Jenny MJ, Woodin BR, Hahn ME and Stegeman JJ (2007) Role of AHR2 in the expression of novel cytochrome P450 1 family genes, cell cycle genes, and morphological defects in developing zebra fish exposed to 3,3',4,4',5-pentachlorobiphenyl or 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Sci. 100: 180-193. PubMed link

Jönsson ME, Orrego R, Woodin BR, Goldstone JV and Stegeman JJ (2007) Basal and 3,3',4,4',5-pentachlorobiphenyl-induced expression of cytochrome P450 1A, 1B and 1C genes in zebrafish. Toxicol Appl Pharmacol. 221: 29-41. PubMed link

Andersson C, Abrahamson A, Brandt I, Jönsson EM, Otte J, Örberg J and Brunström B (2006) Gill filament EROD activity in the three-spined stickleback (Gasterosteus aculeatus L.) as a biomarker for exposure to Ah receptor agonists in the water. Organohalogen Compounds 68: 1259-1261.

Jönsson EM, Abrahamson A, Brunström B and Brandt I (2006) Cytochrome P4501A induction in rainbow trout gills and liver following exposure to waterborne indigo, benzo[a]pyrene and 3,3',4,4',5-pentachlorobiphenyl. Aquat Toxicol. 79: 226-232. PubMed link

Jönsson ME, Carlsson C, Smith RW and Pärt P (2006) Effects of copper on CYP1A activity and epithelial barrier properties in the rainbow trout gill. Aquat Toxicol. 79: 78-86. PubMed link

Jönsson M (2004) A gill filament EROD assay: Development and application in environmental monitoring. Doctoral thesis. Department of Environmental Toxicology. Uppsala University.

Jönsson ME, Brunström B, Ingebrigtsen K and Brandt I (2004) Cell-specific CYP1A expression and benzo[a]pyrene adduct formation in gills of rainbow trout (Oncorhynchus mykiss) following CYP1A induction in the laboratory and in the field. Environ Toxicol Chem. 23: 874-882. PubMed link

Jönsson M, Abrahamson A, Brunström B, Brandt I, Ingebrigtsen K and Jörgensen EH (2003) EROD activity in gill filaments of anadromous and marine fish as a biomarker of dioxin-like pollutants. Comp Biochem Physiol C Toxicol Pharmacol. 136: 235-243. PubMed link

Jönsson EM, Brandt I and Brunström B (2002) Gill filament-based EROD assay for monitoring waterborne dioxin-like pollutants in fish. Environ Sci Technol. 36: 3340-3344. PubMed link

Smith R, Jönsson M, Houlihan D and Pärt P (2001) Minimising aerobic respiratory demands could form the basis to sub-lethal copper tolerance by rainbow trout gill epithelial cells in vitro. Fish Physiology and Biochemistry. 24: 157-169. Abstract

Smith RW, Blaney SC, Dowling K, Sturm A, Jönsson M and Houlihan DF (2001) Protein synthesis costs could account for the tissue-specific effects of sub-lethal copper on protein synthesis in rainbow trout (Oncorhynchus mykiss). Aquat Toxicol. 53: 265-277. PubMed link